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Tag Archives: Law

The AstraZeneca trial is allowed to resume

Federal health regulators have decided to allow the resumption of U.S. studies of a leading Covid-19 vaccine candidate from AstraZeneca PLC and the University of Oxford, according to a person familiar with the matter and materials reviewed by The Wall Street Journal. Here is the WSJ article, no real explanation given by either the company or the FDA. The post The AstraZeneca trial is allowed to resume appeared first on Marginal REVOLUTION.

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The window tax

The window tax in Great Britain (1696–1851) provides a remarkable case of tax-induced distortions in resource allocation. Tax liabilities on dwelling units depended on the number of windows in the unit. As a consequence, people boarded up windows and built houses with very few windows, to the detriment of both health and aesthetics. Using data from local tax records on individual houses, the analysis in the paper finds compelling evidence of such tax-avoidance and goes on to make a rough...

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My Conversation with Michael Kremer

Self-recommending, here is the transcript, audio, and video.  Here is part of the summary: Michael joined Tyler to discuss the intellectual challenge of founding organizations, applying methods from behavioral economics to design better programs, how advanced market commitments could lower pharmaceutical costs for consumers while still incentivizing R&D, the ongoing cycle of experimentation every innovator understands, the political economy of public health initiatives, the importance of...

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Should government improve the quality of its software?

From a GitHub repository: This GitHub repository is a back up of my FAERSFix scripts. The FDA Adverse Effect Reporting System is a horrifically dysfunctional quagmire of shockingly bad data. The data is not just bad for severe epistemological reasons, it is also poorly organized and riddled with flagrant absurd errors. These scripts smooth over the very messy process of acquiring and basic debugging of the data. At the end of the process a user can arrive at a local repository of the FAERS...

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The AstroZeneca saga, according to one source

This seems unconfirmed, and do note some sources in the story do not believe this account, but here goes: AstraZeneca, whose Phase 3 coronavirus vaccine clinical trial has been on hold for more than a month, did not get critical safety data to the US Food and Drug Administration until last week, according to a source familiar with the trial. The FDA is considering whether to allow AstraZeneca to restart its trial after a participant became ill. At issue is whether the illness was a fluke, or...

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From the comments, on AstraZeneca vaccine trial resumption

America is really, really messed up. The only place with such intensely wasteful discussions about a disease is the U.S. And it is getting increasingly easy to ignore the U.S. as the world continues to respond to this pandemic. And it is not just the British based trial. This is from Reuters on Sept. 14 – “Clinical trials for the coronavirus vaccine being developed by AstraZeneca PLC and Oxford University resumed in Brazil on Monday after the country’s health regulator got...

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Model this

Nancy Pelosi warned that a Covid-19 vaccine should not be authorised for use in the US based on data from British trials, amid fears that the Trump administration is planning to rush out an inoculation before election day. The Democratic speaker of the House of Representatives on Friday cast doubt on the British system for testing and approving medicines, further politicising the race to develop a vaccine for Covid-19. “We need to be very careful about what happens in the UK. We have very...

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Monoclonal antibodies are doing very well

In the study, 112 patients received 2.8 grams of each of the antibodies, and 156 received placebo. The difference in viral load was statistically significant at day 11, unlike some doses of Lilly’s single-antibody cocktail. There was also a statistically significant reduction in viral levels three days and seven days after infection. The treatment also improved symptoms, according to a scored questionnaire, and resulted in fewer hospital and emergency room visits. Visits to the hospital or ER...

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My Conversation with Audrey Tang

For me one of the most fun episodes, here is the audio, video, and transcript.  And here is the longer than ever before summary, befitting the chat itself: Audrey Tang began reading classical works like the Shūjīng and Tao Te Ching at the age of 5 and learned the programming language Perl at the age of 12. Now, the autodidact and self-described “conservative anarchist” is a software engineer and the first non-binary digital minister of Taiwan. Their work focuses on how social and digital...

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Why are North and South India so different on gender?

From Alice Evans: Region is a strong predictor of female survival, literacy, autonomy, employment, and independent mobility. A woman with the exact same household wealth/ caste/ religion will likely have more autonomy if she lives in the South. It does not seem to be a function of wealth, nor was colonialism a major factor.  And cousin marriage, which is more prevalent in the south?  Alice notes: Southern women may have gained autonomy despite cousin marriage, not because of it. Islam,...

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